Alcohol, Drugs and Medication in Pregnancy
The Long Term Outcome for the Child
Product Type: Print Edition (Complete Book)
Series: Clinics in Developmental Medicine
Publication date: January 2011
Page count: 256
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This book documents the consequences of the exposure of infants to the influence of intrauterine chemicals.
In setting out the evidence for these outcomes, the authors demonstrate that decisions about care and management can and should be made as early as possible. This should allow professionals to provide protective management and prevent the delays that are so often seen in this area of medical and social care.
The international team of contributors sets out to inform the reader of the potential risks to infants exposed to a range of intrauterine chemicals that are potentially neuroactive, including medicinal drugs such as antiepileptics, antidepressants and antipsychotics, as well as drugs of abuse, including alcohol, opiates, and recreational drugs such as cannabis and tobacco.
They review the teratogenic action of some of the chemical processes and the relationship of exposure to the stage of pregnancy. Some agents alter anatomic structure; others alter the chemical balance of neurotransmitters and may thus alter the regulation of brain function, with profound effects on the child’s behaviour and propensity to behavioural disturbances.
The book explores strategies to support these children and those who care for them, including statutory agencies.
Paediatricians, neonatologists, obstetricians, gynaecologists, child and adolescent psychiatrists and psychologists, those working in child care and child protection.
Clinics in Developmental Medicine No. 188
Philip Preece is a consultant paediatrician with training in neurodisability. He manages a range of children with autism spectrum disorders, attention-deficit hyperactivity disorder, and learning difficulties. He has developed an interest in the outcome of infants exposed to prenatal drugs, both medicinal and recreational, as part of his work assessing children prior to adoption.
Ed Riley served as Chair of the National Task Force on Fetal Alcohol Syndrome/Fetal Alcohol Effect. He currently serves as the Steering Committee Co-Chair of the Fetal Alcohol Spectrum Disorders Center for Excellence. He has been President of the Research Society on Alcohol, the Fetal Alcohol Study Group, and the Behavioral Teratology Society. He has served as Associate Editor of the Journal of Studies on Alcohol, and is on the Editorial Boards of Alcoholism: Clinical and Experimental Research and the Psychological Record. He has received numerous awards for his scholarship and service, most recently the Research Society on Alcoholism Distinguished Researcher Award.
- AUTHORS' APPOINTMENTS vii
- 1. INTRODUCTION 1
- Philip M Preece
- SECTION 1.
- NEUROTERATOGENESIS: EPIDEMIOLOGY AND PATHOLOGY
- 2. EPIDEMIOLOGY OF DRUG AND ALCOHOL USE DURING PREGNANCY 11
- Ron Gray
- 3. NORMAL AND ABNORMAL EMBRYOGENESIS OF THE MAMMALIAN BRAIN 23
- Kathy K Sulik, Shonagh K OÄôLeary-Moore, Elizabeth A Godin
- and Scott E Parnell
- SECTION 2.
- LONG-TERM EFFECTS OF MAJOR PRESCRIBED MEDICATIONS
- 4. EPILEPSY IN PREGNANCY AND THE EFFECT OF PRENATAL ANTIEPILEPTIC MEDICATION 44
- Jill Clayton-Smith and Gus Baker
- 5. NEURODEVELOPMENT OF CHILDREN EXPOSED TO ANTIDEPRESSANT AND ANTIPSYCHOTIC MEDICATIONS DURING PREGNANCY 56
- Irene Nulman, Sara Citron, Michelle Todorow and
- Elizabeth Uleryk
- SECTION 3.
- LONG-TERM EFFECTS OF DRUGS OF ABUSE
- 6. DIAGNOSIS OF FETAL ALCOHOL SYNDROME: EMPHASIS ON EARLY DETECTION 85
- Margaret Barrow and Edward P Riley
- 7. THE EFFECTS OF PRENATAL ALCOHOL EXPOSURE ON BRAIN AND BEHAVIOUR 108
- Christie L McGee Petrenko and Edward P Riley
- 8.EFFECT OF DRUGS OF ABUSE ON THE FETUS: COCAINE AND OPIATES INCLUDING HEROIN 130
- Lynn T Singer and Sonia Minnes
- 9. CANNABIS USE DURING PREGNANCY: ITS EFFECTS ON
- OFFSPRING FROM BIRTH TO YOUNG ADULTHOOD 153
- Peter A Fried
- 10. IN UTERO EXPOSURE TO THE POPULAR 'RECREATIONAL' DRUGS
- MDMA (ECSTASY) AND METHAMPHETAMINE (ICE, CRYSTAL):
- PRELIMINARY FINDINGS 169
- Derek G Moore, John J D Turner, Julia E Goodwin, Sarah E Fulton, Lynn T Singer and Andrew C Parrott
- 11. THE SHORT-TERM AND LONG-TERM DEVELOPMENTAL CONSEQUENCES OF MATERNAL SMOKING DURING PREGNANCY 183
- Kate E Pickett and Lauren S Wakschlag
- SECTION 4.
- INTERVENTION STRATEGIES TO REDUCE THE IMPACT OF DRUGS AND
- ALCOHOL IN PREGNANCY
- 12. MANAGEMENT OF THE EFFECTS OF PRENATAL DRUGS IN CHILDREN OF DRUG-ABUSING PARENTS 197
- Faye Macrory and Michael Murphy
- 13. PRENATAL AND POSTNATAL INTERVENTION STRATEGIES FOR
- ALCOHOL-ABUSING MOTHERS IN PREGNANCY 217
- Ann P Streissguth and Therese M Grant
- 14. COGNITIVE AND BEHAVIOURAL INTERVENTIONS TO AMELIORATE THE EFFECTS OF FETAL ALCOHOL SPECTRUM DISORDERS IN CHILDREN AND ADOLESCENTS: PROMOTING
- POSITIVE OUTCOMES 234
- Wendy O Kalberg and Julie Gelo
- 15. FETAL TERATOGEN SYNDROMES: PSYCHIATRIC ASPECTS AND
- MANAGEMENT 252
- David J Bramble and Raja A S Mukherjee
- 16. RECOMMENDED MANAGEMENT OF COMMON MEDICAL PROBLEMS IN PREGNANCY: ADVICE FROM SPECIALIST AGENCIES 271
- Evelyne Jacqz-Aigrain and Philip M Preece
- INDEX 280
- COLOUR PLATE SECTION
'For those new to this area and for students learning about this subject, this book offers an excellent, balanced overview of risks and management strategies. It is a book that should be on the shelf or in the library of anyone educating people in this topic area and would be a excellent starting point for people wanting to learn about these disorders.' Raja AS Mukherjee, Acta Paediatrica, 2011
'This book will be of value to those working directly or indirectly with pregnant women or their partners, young children of parents or potential parents who use drugs of abuse (or specific prescribed drugs). They could be clinicians (of medical, nursing, psychological or social welfare backgrounds), researchers, students, managers or policy makers (providers of services). Although it has a strong scientific basis, the content is useful and understandable irrespective of the readerís scientific background. Overall, the authors have provided an excellent foundation to facilitate an understanding of the long-term outcomes of alcohol, drugs and medication use in pregnancy and the challenges involved with the management of the families involved.' Lucy Harvey-Dodds, Drug and Alcohol Review
'This book will be of interest to professionals who work in the fields of midwifery, obstetrics, paediatrics, general practice and adolescent addiction. The information provided is comprehensive and based on clearly cited research evidence making it a reliable and useful resource. The consequences of intrauterine exposure to prescribed drugs and substances of abuse are extensively explored and well documented, and the modification and management strategies of these during ante-, peri- and postnatal stages to improve outcomes are clearly presented.' Jess Dorrett, Nursing Children and Young People, 2012
'This book tackles a common problem from a slightly different angle. It is comprehensive and not designed for quick and easy reference. The chapters on recreational drugs are standouts. Overall it is an aesthetically pleasing textbook and a nice addition to the literature.' Anthony Shanks, MD, Indiana University School of Medicine
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