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1898683387

Central Nervous System Tumours of Childhood (ebook)

Product Type: PDF (Complete Book)

ISBN: 9781898683735

Eddy Estlin (Editor), Stephen Lowis (Editor)

Series: Clinics in Developmental Medicine

Edition: 1st

Publication date: January 2005

Page count: 372

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Ranging from epidemiology and neuroimaging through the general principles of surgery and radiotherapy/chemotherapy to issues of palliative care and quality of life, this concise, broad-ranging and practical text covers all clinical aspects of central nervous system tumours in children.

It provides an overview of current important issues in diagnosis and management, and focuses on important areas of research, with an emphasis on the areas likely to impact on clinical practice.

It is essential reading for paediatric oncologists, medical and clinical oncologists, neurosurgeons, and paediatricians involved in the care of children with brain tumours, trainees in these and related specialties, specialist nurses and paramedical staff.

Clinics in Developmental Medicine No. 166

Eddy Estlin (Editor)

Eddy Estlin is the Macmillan Consultant in Paediatric Oncology at the Royal Manchester Children's Hospital, Manchester, UK.

Stephen Lowis (Editor)

Stephen Lowis is the Macmillan Consultant in Paediatric Oncology at the Hospital for Sick Children, Bristol, UK.

  • AUTHORS' APPOINTMENTS vii
  • SECTION ONE: INTRODUCTION AND OVERVIEW OF DIAGNOSIS, 1
  • BIOLOGY AND THERAPY
  • 1. INTRODUCTION 3
  • Eddy Estlin and Stephen Lowis
  • 2. THE EPIDEMIOLOGY OF PAEDIATRIC CNS TUMOURS 7
  • GA Amos Burke
  • 3. PAEDIATRIC CNS TUMOURS: NEUROIMAGING 18
  • Shelley Renowden
  • 4. PATHOLOGY AND MOLECULAR ONCOLOGY OF CHILDHOOD 107
  • CNS TUMOURS
  • Lucy B Rorke-Adams and Jaclyn A Biegel
  • 5. MOLECULAR APPROACHES TO THE UNDERSTANDING AND
  • TREATMENT OF CHILDHOOD CNS TUMOURS 129
  • Richard J Gilbertson
  • 6. SURGICAL MANAGEMENT OF CNS TUMOURS IN THE
  • PAEDIATRIC POPULATION 151
  • Jerard Ross and John Thorne
  • 7. GENERAL PRINCIPLES OF RADIOTHERAPY 163
  • Eddy Estlin and Stephen Lowis
  • 8. GENERAL PRINCIPLES OF CHEMOTHERAPY 178
  • Eddy Estlin
  • 9. MANAGEMENT OF COMPLICATIONS AT PRESENTATION FOR
  • CHILDREN WITH CNS TUMOURS 190
  • Stephen Lowis
  • SECTION TWO: CNS TUMOURS OF CHILDHOOD 201
  • 10. LOW-GRADE AND HIGH-GRADE ASTROCYTOMA 203
  • Eddy Estlin and Stephen Lowis
  • 11. EPENDYMOMA 221
  • Ute Bartels, Douglas J Hyder, Annie Huang and Eric Bouffet
  • 12. BRAINSTEM TUMOURS 234
  • Carolyn R Freeman and Jean-Pierre Farmer
  • 13. PRIMITIVE NEUROECTODERMAL TUMOURS 245
  • Stephen Lowis
  • 14. INTRACRANIAL GERM CELL TUMOURS 258
  • Susanne J Rogers and Frank H Saran
  • 15. CHOROID PLEXUS PAPILLOMA AND CARCINOMA 273
  • Stephen Lowis
  • 16. CRANIOPHARYNGIOMA 277
  • Eddy Estlin
  • 17. MIXED NEURONAL TUMOURS 284
  • Eddy Estlin
  • 18. SPINAL CORD TUMOURS IN CHILDREN 289
  • Douglas J Hyder, Peter B Dirks, Ute Bartels and Eric Bouffet
  • 19. METASTATIC DISEASE AFFECTING THE CNS 287
  • Stephen Lowis
  • SECTION THREE: LATE EFFECTS, REHABILITATION AND PALLIATIVE
  • CARE 301
  • 20. LATE EFFECTS OF CNS TUMOURS 303
  • Adam Glaser and Gary Butler
  • 21. AN OVERVIEW OF CEREBRAL FUNCTIONING AND ITS
  • APPLICATION IN THE DEVELOPING BRAIN 314
  • Andrew Curran
  • 22. PALLIATIVE CARE 331
  • Erica Mackie
  • SECTION FOUR: SUMMARY 343
  • 23. CONCLUSIONS AND FUTURE DIRECTIONS 345
  • Eddy Estlin and Stephen Lowis
  • INDEX