Chapter 1 AUTISM book ICNA7 Tuchman

Autism: a Neurological Disorder of Early Brain Development – (Chapter 1) – Where We Are: Overview and Definitions (free ebook)

Product Type: PDF (Sub-Section of Book)

Series: International Reviews of Child Neurology Series

Edition: 1st

Publication date: July 2008

Page count: 33

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Chapter 1  – Where We Are: Overview and Definitions by Isabelle Rapin and Roberto F Tuchman from Autism: a Neurological Disorder of Early Brain Development

About the Complete Book

Written by child neurologists, this comprehensive, multi-authored volume on autism systematically discusses the classification, epidemiology and neurobiology of autism.

Autism lacks a unique etiology or specific pathology, so the behaviorally defined social deficits, language impairments and repetitive behaviors that define autism are explored from a developmental neurology perspective. The evidence suggesting that autism is a disorder of neuronal development is reviewed by experts on the genetics, neuroanatomy and neuroradiology, neurochemistry, immunology, and neurophysiology of autism. Chapters provide comprehensive reviews of the common neurological problems associated with autism such as epilepsy, sleep disturbances and motor and sensory deficits.

Neuropsychological assessment, medical and psychopharmacologic management, educational and behavioral interventions, and outcome are discussed within the clinical content of the practising neurologist. The research agenda needed to understand the neurology of autism is emphasized throughout the book and in the conclusion.

International Review of Child Neurology Series No. 7

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Isabelle Rapin and Roberto F Tuchman (Authors) Roberto Tuchman (Editor)

Roberto F Tuchman

Roberto F Tuchman is Director of Neurology at  Nicklaus Children's Hospital, Miami, Florida.

Isabelle Rapin (Editor)

Isabelle Rapin

Isabelle Rapin was professor emerita in the Saul R. Korey Department of Neurology and Department of Pediatrics at the Albert Einstein College of Medicine.

  • Full book contents
  • CONTENTS
  • AUTHORS’ APPOINTMENTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . vii
  • FOREWORD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi
  • DEDICATION and ACKNOWLEDGMENTS . . . . . . . . . . . . . . . . . . . . . . . . . . . xii
  • PREFACE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xiii
  • Martha Bridge Denckla
  • 1 WHERE WE ARE: OVERVIEW AND DEFINITIONS. . . . . . . . . . . . . . . . . . 1
  • Isabelle Rapin and Roberto F Tuchman
  • 2 EPIDEMIOLOGY OF AUTISM SPECTRUM DISORDERS . . . . . . . . . . . . 19
  • Edwin Trevathan and Shlomo Shinnar
  • 3 THE SOCIAL DEFICIT IN AUTISM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38
  • Roberto F Tuchman
  • 4 LANGUAGE AND COMMUNICATION: CLINICAL
  • ASSESSMENT AND DIFFERENTIAL DIAGNOSIS . . . . . . . . . . . . . . . . . . 51
  • Isabelle Rapin
  • 5 STEREOTYPIES AND REPETITIVE BEHAVIORS: CLINICAL
  • ASSESSMENT AND BRAIN BASIS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68
  • Jonathan W Mink and David E Mandelbaum
  • 6 NEUROBIOLOGY OF AUTISM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79
  • Michael V Johnston and Mary E Blue
  • 7 GENETIC ASPECTS OF AUTISM. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93
  • Maria T Acosta and Phillip L Pearl
  • 8 NEUROANATOMY AND IMAGING STUDIES . . . . . . . . . . . . . . . . . . . . 115
  • Martha R Herbert and Verne S Caviness, Jr
  • 9 NEUROIMMUNOLOGY AND NEUROTRANSMITTERS IN
  • AUTISM. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141
  • Andrew W Zimmerman, Susan L Connors and Carlos A Pardo-Villamizar
  • 10 ELECTROPHYSIOLOGY AND EPILEPSY IN AUTISM . . . . . . . . . . . . . . 160
  • Kent R Kelley and Solomon L Moshé
  • 11 AUTISM, EPILEPSY AND EEG EPILEPTIFORM ACTIVITY . . . . . . . . . . 174
  • Eliane Roulet-Perez and Thierry Deonna
  • 12 SLEEP AND AUTISM SPECTRUM DISORDERS . . . . . . . . . . . . . . . . . . . 189
  • Beth A Malow and Susan G McGrew
  • 13 ATYPICAL SENSORY/PERCEPTUAL RESPONSIVENESS . . . . . . . . . . . . 202
  • Isabelle Rapin
  • 14 MOTOR DEFICITS IN AUTISM. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 231
  • Jennifer C Gidley Larson and Stewart H Mostofsky
  • 15 PATHOPHYSIOLOGY OF AUTISM; EVALUATION OF SLEEP
  • AND LOCOMOTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 248
  • Masaya Segawa and Yoshiko Nomura
  • 16 NEUROPSYCHOLOGICAL ASSESSMENT: BASIC CONCEPTS
  • AND CLINICAL UTILITY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 265
  • Susan K Klein
  • 17 TREATMENT APPROACHES FOR THE AUTISM SPECTRUM
  • DISORDERS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 281
  • Mark Mintz, Michael Alessandri and Paolo Curatolo
  • 18 OUTCOMES OF CHILDREN WITH AUTISM. . . . . . . . . . . . . . . . . . . . . 308
  • Evdokia Anagnostou and Michael Shevell
  • 19 WHAT WE HAVE LEARNED, WHERE WE NEED TO GO. . . . . . . . . . . 322
  • Roberto F Tuchman and Isabelle Rapin
  • INDEX . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 332

'This book offers a neurobiological orientation for a rational understanding of that seriously impairing, deeply fascinating and equally mysterious spectrum of disorder development. Very well written, straight to the point, contains a good number of excellent tables and it is exciting to read. it is an outstanding, high quality review of issues relating to autism and I recommend it wholeheartedly.' European Journal of Paediatric Neurology, 2007

'The book provides a comprehensive compilation of the main issues in autism, including epidemiology, language, and neurobiology. Of particular note are the excellent chapters by Rapin on assessment of language and by Acosta and Pearl on genetics.' Journal of International Neuropsychological Society, 2007

'Rapin and Tuchman have produced an exceptional survey from the neuroscience viewpoint of the literature pertaining to children with autistic behavior. It is difficult to imagine a child neurologist or developmental pediatrician who would not want to own this volumeómany of them will even consider sending a copy or two to their local child psychiatrist or child development center. Certainly every trainee in neurology, pediatrics, and child psychiatry should read this book. Many child psychologists, social workers, and other persons who interact with behaviorally disturbed children will want to have access to a copy.' Robert J. Baumann, MD, Pediatric Neurology, 2007