Cognition and Behaviour in Childhood Epilepsy, Lagae, Chapter 6 cover

Cognition and Behaviour in Childhood Epilepsy – Chapter 6: Disentangling the Role of Seizures and EEG Abnormalities in the Pathophysiology of Cognitive Dysfunction (ebook)

Product Type: PDF (Sub-Section of Book)

Series: Clinics in Developmental Medicine

Edition: 1st

Publication date: May 2017

Page count: 14

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Chapter 6 – Disentangling the Role of Seizures and EEG Abnormalities in the Pathophysiology of Cognitive Dysfunction

Although seizures are the most striking clinical manifestation of the epilepsies, children with epilepsy are at risk not only for seizures but also for a number of comorbid health problems defined as conditions that occur in children with epilepsy at a higher rate than would be expected by chance. Common comorbidities that occur in children with epilepsy include cognitive dysfunction, such as memory, attention, or processing difficulties; mental health conditions, including depression, anxiety, and oppositional-defiant disorder; and somatic comorbidities, such as sleep disorders and migraines. Epilepsy comorbidities are common and often severe. Many parents of children with epilepsy consider the comorbidities to outweigh the burden of the seizures themselves.

About the book

For many parents, cognitive and behavioral comorbidities, such as ADHD, autism and intellectual disability, are the real burden of childhood epilepsy. This title offers concrete guidance and treatment strategies for childhood epilepsy in general, and for the comorbidities associated with each epilepsy syndrome and their pathophysiology. The book is written by experts in the field with an important clinical experience, while chapters by clinical neuropsychologists provide a strong theoretical background.

Readership: Epileptologists, Paediatric Neurologists, Paediatricians and Neuropsychologists.

Jonathan K Kleen and Gregory L Holmes (Authors) Lieven Lagae (Editor)

Lieven Lagae is Professor of Paediatric Neurology at the University of Leuven, Belgium (KUL), Head of the Paediatric Neurology Department of the KUL University Hospitals, and Director of the Childhood Epilepsy Program at the KUL University Hospitals. He is the current President of the European Pediatric Neurology Society and serves as an elected Board Member of the International Child Neurology Association (ICNA). From 2004 to 2015 he was the Editor-in-Chief of the European Journal of Paediatric Neurology. His research interests include translational research in zebrafish models of epilepsy, new antiepileptic drugs for childhood epilepsy, brain stimulation and preventive treatment of epilepsy in tuberous sclerosis.

  • Full book contents
  • AUTHORS’ APPOINTMENTS
  • PREFACE
  • 1. COGNITIVE DIFFICULTIES IN CHILDREN WITH EPILEPSY: SOURCES AND IMPLICATIONS
  • ANNE T BERG
  • 2. INTRODUCTORY REMARKS ON NEUROPSYCHOLOGICAL TESTING IN CHILDHOOD EPILEPSY
  • AGATHE LAURENT, FAUSTINE ILSKI-LECOANET AND ALEXIS ARZIMANOGLOU
  • 3. BEHAVIOURAL PROBLEMS IN CHILDHOOD EPILEPSY
  • MELISSA FILIPPINI AND GIUSEPPE GOBBI
  • 4. THE INTERACTION BETWEEN CHILDHOOD-ONSET EPILEPSY AND COGNITON: LONG-TERM FOLLOW UP
  • PETER CAMFIELD AND CAROL CAMFIELD
  • 5. USE OF FUNTIONAL IMAGING TO STUDY COGNITIVE FUNCTIONS
  • MADISON M BERL AND LEIGH N SEPETA
  • 6. DISENTANGLING THE ROLE OF SEIZURES AND EEG ABNORMALITIES IN THE PATHOPHYSIOLOGY OF COGNITIVE DYSFUNCTION
  • JONATHAN K KLEEN AND GREGORY L HOLMES
  • 7. CHRONIC COGNITIVE EFFECTS OF ANTIEPILEPTIC DRUGS IN CHILDHOOD EPILEPSY
  • ALBERT P ALDENKAMP, WILLEM LAVRIJSSEN AND DOMINIQUE IJFF
  • 8. OUTCOME AFTER NEONATAL SEIZURES
  • RENÉE A SHELLHAAS AND COURTNEY J WUSTHOFF
  • 9. “BENIGN” CHILDHOOD EPILEPSY SYNDROMES: WHY DO SOME PRESENT WITH LEARNING PROBLEMS?
  • STÉPHANE AUVIN
  • 10. “BENIGN” INFANTILE EPILEPSIES: IMPACT ON LATER COGNITION AND BEHAVIOUR
  • FEDERICO VIGEVANO AND ROMINA MOAVERO
  • 11. INFANTILE SPASMS: EARLY TREATMENT MAY IMPROVE NEURODEVELOPMENTAL OUTCOMES
  • ANDREW LUX
  • 12. DRAVET SYNDROME: MORE THAN SEIZURES
  • EMMA LOSITO AND RIMA NABBOUT
  • 13. THE EPILEPTIC SYNDROMES WITH CONTINUOUS SPIKES AND WAVES DURING SLOW-WAVE SLEEP
  • PATRICK VAN BOGAERT AND XAVIER DE TIÉGE
  • 14. GLOBAL PROGNOSIS AND NEUROPSYCHOLOGICAL OUTCOME OF LENNOX–GASTAUT SYNDROME
  • ALEXIS ARZIMANOGLOU, ELENI PANAGIOTAKAKI AND ALIA RAMIREZ CAMACHO
  • 15. COGNITIVE AND BEHAVIOURAL OUTCOMES AFTER EPILEPSY SURGERY IN CHILDREN
  • MONIQUE MJ VAN SCHOONEVELD, KEES PJ BRAUN AND J HELEN CROSS