The Epilepsy-Aphasia Spectrum, Deonna, Roulet-Perez, Chapter 5 cover

Epilepsy-Aphasia Spectrum – Chapter 5: The Different Clinical Facets of Landau–Kleffner Syndrome (ebook)

This chapter is part of The Epilepsy-Aphasia Spectrum

From Landau-Kleffner Syndrome to Rolandic Epilepsy

Product Type: PDF (Sub-Section of Book)

Thierry Deonna (Author), Eliane Roulet-Perez (Author)

Series: Clinics in Developmental Medicine

Edition: 1st

Publication date: November 2016

Page count: 26

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Chapter 5 – The Different Clinical Facets of Landau–Kleffner Syndrome

This chapter is devoted to an analysis of the two main dimensions of Landau–Kleffner syndrome (LKS): the epilepsy and the language. As an introduction and illustration, we present the case histories of two of our patients followed from childhood to adulthood with completely different clinical presentations and courses that highlight the different facets of LKS and the importance of long-term studies.

About the book

Landau Kleffner syndrome (LKS) is a rare childhood epilepsy, characterised by a sudden or gradual loss of ability to understand or express language.  Written by two  world-renowned  authorities on childhood epilepsy, this book is aimed at the large range of professionals involved in the diagnosis, therapy and rehabilitation of children on the EAS. The book includes vivid first-hand accounts of the impact of language loss by adults who have grown up with LKS.

Readership: epileptologists, psychiatrists, psychologists, neuropsychologists, speech and language therapists and trainees in those areas.

Thierry Deonna (Author)

Thierry Deonna is Emeritus Professor of Neurology at the University of Lausanne, Switzerland where he founded and headed the Child Neurology Unit at the University of Lausanne Children’s Hospital. His main areas of interest are childhood epilepsy and developmental disorders. He has written over 150 articles and book chapters on general child neurology, language disorders and epilepsy.

Eliane Roulet-Perez (Author)

Eliane Roulet-Perez is Professor of Paediatric Neurology at the Faculty of Biology and Medicine, University of Lausanne, Switzerland. She has been head of the Paediatric Neurology and Neurorehabilitation Unit at the Centre Hospitalier Universitaire Vaudois Lausanne since 2003. Professor Roulet-Perez has published  many articles on her main interests : Landau-Kleffner syndrome, epileptic encephalopathy with continuous-spike waves during sleep and autism and epilepsy. She is currently a member of the International League Against Epilepsy Commission on Classification and Terminology of Seizures and Epilepsies.

  • Full book contents
  • 1 INTRODUCTION
  • 2 HISTORY OF LANDAU-KLEFFNER SYNDROME (LKS)
  • 3 CLASSIFICATIONS ISSUES
  • 4 SPEECH PERCEPTION AND BRAIN ORGANIZATION OF LANGUAGE: RELEVANT FEATURES FOR LKS AND EAS
  • 5 THE DIFFERENT CLINICAL FACETS OF LKS
  • 6 DEVELOPMENTAL ASPECTS OF LKS /EAS AND THE OVERLAP WITH DEVELOPMENTAL LANGUAGE DISORDER AND AUTISM SPECTRUM DISORDER
  • 7 EVOLUTION OF LKS . SHORT – MID AND LONG TERM OUTCOME
  • 8 FROM ROLANDIC EPILEPSY TO LANDAU-KLEFFNER SYNDROME
  • 9 LABORATORY (EEG,BRAIN IMAGING, GENETICS AND NEUROIMMUNOLOGY ) INVESTIGATIONS FOR LKS/EAS
  • 10 PHYSIOPATHOLOGY OF SPEECH, LANGUAGE AND OTHER PROLONGED EPILEPTIC DYSFUNCTION IN LKS, ECSWS AND RELATED SYNDROMES
  • 11 FUNCTIONAL NEUROIMAGING INVESTIGATIONS IN IDIOPATHIC FOCAL EPILEPSIES OF CHILDHOOD WITH COGNITIVE AND BEHAVIOURAL IMPAIRMENT. XAVIER DE TIÈGE, SERGE GOLDMAN & PATRICK VAN BOGAERT
  • 12 DRUG MANAGEMENT OF COGNITIVE IMPAIRMENTS IN LKS AND OTHER EAS SYNDROMES
  • 13 SPEECH AND LANGUAGE, EDUCATIONAL AND PSYCHOLOGICAL REMEDIATION
  • 14 PERSONAL TESTIMONIES AND UNPUBLISHED CASES
  • 15 SUMMARY AND CONCLUSIONS

'The experienced authors of this book are to be commended for their comprehensive overview of the epilepsyaphasia spectrum, which presents a challenge in both identification and management despite having been described for decades. The book is illustrated with many case studies that enrich the more academic content and provide a resource for future hypothesis-driven research. A particular strength is the longitudinal follow-up into adult life of many cases originally presenting in childhood and the emphasis on the ‘whole person’; hence, this book is appropriate for primary care physicians, paediatricians, neurologists, psychiatrists, allied health professionals, and educationalists.' Michael Absoud and Gillian Baird, Developmental Medicine and Child Neurology, March 2017

'This is a very readable summary of the literature and comprehensive knowledge gained through a career of study of acquired epileptic aphasia. The authors make the convincing case that the Landau-Kleffner syndrome as historically taught is but a severe form of what should be thought of as epilepsy-aphasia spectrum disorder of childhood. Included throughout the book are the limits of current knowledge and suggestions of areas of further research needed. This book was very helpful to understanding this area and why it is hard to understand. This would be recommended reading for anyone with questions about the epilepsy-aphasia link.' AACPDM Newsletter, Summer 2017