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Neurodevelopmental Disabilities: Clinical and Scientific Foundations

Product Type: Print Edition (Complete Book)

ISBN: 9781898683674

Michael Shevell (Editor)

Series: International Review of Child Neurology Series

Edition: 1st

Publication date: July 2009

Page count: 483

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Neurodevelopmental disabilities are a common problem in child health.

This book takes a comprehensive approach to addressing these often challenging clinical diagnoses. In particular, it focuses on the two most common of childhood neurodevelopmental disabilities: global developmental delay and developmental language impairment.

It seeks to put forward our present conceptualization of these entities as well as their proper evaluation and assessment and diagnosis from a variety of perspectives. It also provides details on our current understanding of the scientific basis of these disorders and their underlying causes. Issues related to medical management, rehabilitation, and eventual outcomes are also addressed in a detailed way.

The book has wide appeal to those in paediatrics, developmental paediatrics, child neurology, and paediatric rehabilitation. Its geographic appeal includes both developed and developing nations as some chapters are devoted to the particular issues faced in underdeveloped countries.

The book’s focus on both clinical and scientific aspects is invaluable in this field. It also provides extensive information in a single source relating to often-overlooked areas such as medical management, rehabilitation, public policy, and ethics.

International Review of Child Neurology Series No. 10

Michael Shevell (Editor)

Michael Shevell

Michael Shevell is a Professor in the Departments of Neurology/Neurosurgery and Pediatrics at McGill University. He is also currently Director of the Division of Pediatric Neurology at the Montreal Children’s Hospital-McGill University Health Center.

He has an ongoing research interest in children with or at risk for neurodevelopmental disabilities. He was Chairman of the Xth World Congress of the International Child Neurology Association held in Montreal in June 2006. He is the long-standing Chair of the Ethics Committee of the Child Neurology Society and is a currently a Member of the Executive Board of the International Child Neurology Association and former President of the Canadian Association of Child Neurology.

  • AUTHORS’ APPOINTMENTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . viii
  • PREFACE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi
  • Michael Shevell
  • AN OVERVIEW OF NEURODEVELOPMENTAL DISABILITY
  • 1 CONCEPTS AND DEFINITIONS IN
  • NEURODEVELOPMENTAL DISABILITY . . . . . . . . . . . . . . . . . . . . . . 1
  • Michael Shevell
  • 2 THE EPIDEMIOLOGY OF SELECTED
  • NEURODEVELOPMENTAL DISABILITIES –
  • AN OVERVIEW . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
  • Marshalyn Yeargin-Allsopp and Carolyn Drews-Botsch
  • 3 THE CHANGING PANORAMA OF PRESCHOOL
  • DISABILITY: BIOMEDICAL AND SOCIAL RISKS . . . . . . . . . . . . . . 27
  • Michael E Msall and Jennifer J Park
  • 4 ETHICS AND COMMON MORALITY IN
  • NEURODEVELOPMENTAL DISABILITIES . . . . . . . . . . . . . . . . . . . . 43
  • Michael Shevell
  • 5 POLICY AND GOALS FOR THE FUTURE FOR INDIVIDUALS WITH NEURODEVELOPMENTAL DISABILITIES . . . . . . . . . . . . . . 50
  • David L Coulter
  • 6 CHILDREN WITH DEVELOPMENTAL DISABILITIES IN THE MAJORITY OF THE WORLD . . . . . . . . . . . . . . . . . . . . . . . 70
  • Sally Hartley and Charles RJC Newton
  • DETECTION AND EVALUATION
  • 7 SCREENING FOR DEVELOPMENTAL AND BEHAVIORAL PROBLEMS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85
  • Frances Page Glascoe and Kevin P. Marks
  • 8 ETIOLOGY AND EVALUATION IN
  • NEURODEVELOPMENTAL DISABILITY . . . . . . . . . . . . . . . . . . . . . 106
  • Michael Shevell
  • 9 NOVEL IMAGING TECHNIQUES . . . . . . . . . . . . . . . . . . . . . . . . . . 119
  • Jeff Neil and Terrie Inder
  • SCIENTIFIC BASIS OF NEURODEVELOPMENTAL DISABILITY
  • 10 NEUROBIOLOGY OF SPECIFIC LANGUAGE IMPAIRMENT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 145
  • Richard I Webster
  • 11 EFFECTS OF NEUROLOGIC DISORDERS AT THE SYNAPSE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 173
  • Brian R Christie, Brennan D Eadie, Carl Ernst,
  • Andrea K Titterness, Cristina O Vasuta and Alina J Webber
  • 12 MOLECULAR BASIS OF LEARNING AND MEMORY . . . . . . . . . . 189
  • François Bolduc and Tim Tully
  • 13 NEURONAL PLASTICITY AND DEVELOPMENTAL DISABILITY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225
  • Sheryl L Rimrodt and Michael V Johnston
  • ETIOLOGIC FEATURES
  • 14 CHROMOSOMAL SYNDROMES AND
  • DEVELOPMENTAL DELAY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 241
  • Sara S Cathey and Kenton R Holden
  • 15 INBORN ERRORS OF METABOLISM AND DEVELOPMENTAL DELAY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 265
  • Myriam Srour and Michael Shevell
  • 16 THE CEREBELLUM AND DEVELOPMENT . . . . . . . . . . . . . . . . . . 285
  • Catherine Limperopoulos and Adré du Plessis
  • 17 GENETIC MALFORMATIONS OF CORTICAL DEVELOPMENT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 299
  • Elliott H Sherr
  • 18 PERINATAL ACQUIRED BRAIN INJURY . . . . . . . . . . . . . . . . . . . . . 317
  • Jerome Y Yager and Pierre Gressens
  • 19 NON-PERINATAL ACQUIRED BRAIN INJURY . . . . . . . . . . . . . . . 352
  • David J Michelson and Stephen Ashwal
  • MEDICAL MANAGEMENT, REHABILITATION, HEALTH AND
  • OUTCOMES
  • 20 NEW CONCEPTS IN THE REHABILITATION OF
  • CHILDREN WITH DEVELOPMENTAL DISABILITIES:
  • OCCUPATIONAL THERAPY AND PHYSICAL THERAPY
  • PERSPECTIVES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 394
  • Annette Majnemer and Johanna Darrah
  • 21 EARLY INTERVENTION IN DEVELOPMENTAL DISABILITIES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 410
  • David A Kube and Frederick B Palmer
  • 22 SERVICE UTILIZATION AND HEALTH PROMOTION OF CHILDREN WITH NEURODEVELOPMENTAL
  • DISABILITIES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 426
  • Barbara Mazer and Annette Majnemer
  • 23 CO-MORBID CONDITIONS IN NEURODEVELOPMENTAL
  • DISABILITIES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 442
  • Elysa J Marco
  • 24 OUTCOMES IN CHILDREN WITH DEVELOPMENTAL DISABILITIES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 470
  • Annette Majnemer and Catherine Limperopoulos
  • INDEX . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 483

'This book gives a comprehensive review of scientific basis of neurological conditions with special reference to outcome in brain injured infants. It will be useful for neonatologists, paediatric neurologists and scientists from many other disciplines interested in the foetal and neonatal brain.' Madhuri Kulkarni, Indian J Med Res, 2013

'The text recently published by the International Child Neurology Association, Neurodevelopmental Disabilities: Clinical and Scientific Foundations, serves as a strong step toward encouraging this desired interdisciplinary approach. Developed as a reference manual for physicians, this book provides a well-conceptualized and articulated review of current advances in genetics, molecular biology, imaging, and rehabilitation with regard to the neurodevelopmental disorders.' Scott J. HunterPsycCRITIQUES, 2010

'This multi author book is a most ambitious project aiming to lay the foundations of a scientific basis to clinical and research work developmental disabilities. I think that this book is an essential resource for people working in developmental disability.' Brian Neville, European Journal of Paediatric Neurology, 2010