Books

Subject: Psychiatry and Psychology (including ASD and ADHD)

Series: International Review of Child Neurology Series

Publication date: 07/04/2008

ISBN: 9781898683490

Edition: 1st

Pages: 372

Autism

A Neurological Disorder of Early Brain Development

Roberto Tuchman, Isabelle Rapin (Editors)

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£70.00

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Written by child neurologists, this comprehensive, multi-authored volume on autism systematically discusses the classification, epidemiology and neurobiology of autism.

Autism lacks a unique etiology or specific pathology, so the behaviorally defined social deficits, language impairments and repetitive behaviors that define autism are explored from a developmental neurology perspective. The evidence suggesting that autism is a disorder of neuronal development is reviewed by experts on the genetics, neuroanatomy and neuroradiology, neurochemistry, immunology, and neurophysiology of autism. Chapters provide comprehensive reviews of the common neurological problems associated with autism such as epilepsy, sleep disturbances and motor and sensory deficits.

Neuropsychological assessment, medical and psychopharmacologic management, educational and behavioral interventions, and outcome are discussed within the clinical content of the practising neurologist. The research agenda needed to understand the neurology of autism is emphasized throughout the book and in the conclusion.

International Review of Child Neurology Series No. 7

Roberto F Tuchman
Roberto Tuchman

Roberto F Tuchman is Director of Neurology at  Nicklaus Children’s Hospital, Miami, Florida.

Isabelle Rapin
Isabelle Rapin

Isabelle Rapin was professor emerita in the Saul R. Korey Department of Neurology and Department of Pediatrics at the Albert Einstein College of Medicine.

Other books by Rapin

CONTENTS
AUTHORS’ APPOINTMENTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . vii
FOREWORD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi
DEDICATION and ACKNOWLEDGMENTS . . . . . . . . . . . . . . . . . . . . . . . . . . . xii
PREFACE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xiii
Martha Bridge Denckla
1 WHERE WE ARE: OVERVIEW AND DEFINITIONS. . . . . . . . . . . . . . . . . . 1
Isabelle Rapin and Roberto F Tuchman
2 EPIDEMIOLOGY OF AUTISM SPECTRUM DISORDERS . . . . . . . . . . . . 19
Edwin Trevathan and Shlomo Shinnar
3 THE SOCIAL DEFICIT IN AUTISM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38
Roberto F Tuchman
4 LANGUAGE AND COMMUNICATION: CLINICAL
ASSESSMENT AND DIFFERENTIAL DIAGNOSIS . . . . . . . . . . . . . . . . . . 51
Isabelle Rapin
5 STEREOTYPIES AND REPETITIVE BEHAVIORS: CLINICAL
ASSESSMENT AND BRAIN BASIS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68
Jonathan W Mink and David E Mandelbaum
6 NEUROBIOLOGY OF AUTISM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79
Michael V Johnston and Mary E Blue
7 GENETIC ASPECTS OF AUTISM. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93
Maria T Acosta and Phillip L Pearl
8 NEUROANATOMY AND IMAGING STUDIES . . . . . . . . . . . . . . . . . . . . 115
Martha R Herbert and Verne S Caviness, Jr
9 NEUROIMMUNOLOGY AND NEUROTRANSMITTERS IN
AUTISM. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141
Andrew W Zimmerman, Susan L Connors and Carlos A Pardo-Villamizar
10 ELECTROPHYSIOLOGY AND EPILEPSY IN AUTISM . . . . . . . . . . . . . . 160
Kent R Kelley and Solomon L Moshé
11 AUTISM, EPILEPSY AND EEG EPILEPTIFORM ACTIVITY . . . . . . . . . . 174
Eliane Roulet-Perez and Thierry Deonna
12 SLEEP AND AUTISM SPECTRUM DISORDERS . . . . . . . . . . . . . . . . . . . 189
Beth A Malow and Susan G McGrew
13 ATYPICAL SENSORY/PERCEPTUAL RESPONSIVENESS . . . . . . . . . . . . 202
Isabelle Rapin
14 MOTOR DEFICITS IN AUTISM. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 231
Jennifer C Gidley Larson and Stewart H Mostofsky
15 PATHOPHYSIOLOGY OF AUTISM; EVALUATION OF SLEEP
AND LOCOMOTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 248
Masaya Segawa and Yoshiko Nomura
16 NEUROPSYCHOLOGICAL ASSESSMENT: BASIC CONCEPTS
AND CLINICAL UTILITY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 265
Susan K Klein
17 TREATMENT APPROACHES FOR THE AUTISM SPECTRUM
DISORDERS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 281
Mark Mintz, Michael Alessandri and Paolo Curatolo
18 OUTCOMES OF CHILDREN WITH AUTISM. . . . . . . . . . . . . . . . . . . . . 308
Evdokia Anagnostou and Michael Shevell
19 WHAT WE HAVE LEARNED, WHERE WE NEED TO GO. . . . . . . . . . . 322
Roberto F Tuchman and Isabelle Rapin
INDEX . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 332

'Rapin and Tuchman have produced an exceptional survey from the neuroscience viewpoint of the literature pertaining to children with autistic behavior. It is difficult to imagine a child neurologist or developmental pediatrician who would not want to own this volumeómany of them will even consider sending a copy or two to their local child psychiatrist or child development center. Certainly every trainee in neurology, pediatrics, and child psychiatry should read this book. Many child psychologists, social workers, and other persons who interact with behaviorally disturbed children will want to have access to a copy.'

Robert J. Baumann, MD, Pediatric Neurology, 2007

'The book provides a comprehensive compilation of the main issues in autism, including epidemiology, language, and neurobiology. Of particular note are the excellent chapters by Rapin on assessment of language and by Acosta and Pearl on genetics.'

Journal of International Neuropsychological Society, 2007

'This book offers a neurobiological orientation for a rational understanding of that seriously impairing, deeply fascinating and equally mysterious spectrum of disorder development. Very well written, straight to the point, contains a good number of excellent tables and it is exciting to read. it is an outstanding, high quality review of issues relating to autism and I recommend it wholeheartedly.'

European Journal of Paediatric Neurology, 2007

Autism: a Neurological Disorder of Early Brain Development – Chapter 1: Where We Are: Overview and Definitions (free ebook) - £0