Autism is not a single disease but a syndrome of different diseases. In this completely reworked and updated third edition, two world authorities, Christopher Gillberg and Mary Coleman, address the difficulties this presents for clinical diagnosis with diagnostic aids and clear guidelines for medical evaluation. Epidemiology, neuropsychological studies and behavior complexes, such as self-injury, are reviewed in detail, and the authors give a detailed explanation of what is known about the molecular biology and genetics of autism. Epilepsy and electrophysiological studies are also covered, as well as biochemistry, endocrinology, immunology, brain imaging and neuropathology. The available medical therapies are reviewed, along with an update on what is known about other interventions, such as psychoeducational and behavioral modification procedures. The book concludes with an integration of current knowledge from diverse fields. This is an essential text for clinicians and will also be of interest to parents of autistic children.
Clinics in Developmental Medicine No. 153/4
2. Clinical diagnosis
3. Asperger syndrome
4. Diagnosis in infancy
5. Clinical course in childhood and adolescence
6. Adults with autism
7. Additional behaviors seen in individuals with autism
8. The epidemiology of autism and its spectrum disorders
9. Neuropsychology in autism and its spectrum disorders
10. The disease entities of autism
11. Double syndromes
12. Epilepsy and electrophysiology
13. Biochemistry, endocrinology and immunology
14. Structural information- From brain imaging and neuropathology
15. The genetics of autism
16. The first neuropsychiatric assessment
17. Medical therapies
18. Other interventions
19. The neurology of autism
Appendix 1: Glossary of genetic terms
Appendix 2: Chapter for persons with autism
'The new comprehensive edition of this book covers all aspects of the subject from the most recent findings to the features of the disorder, making it an indispensable and practical reference text for physicians involved in the diagnosis and treatment of autism-related disorders.'
Masutomo Miyao, Brain & Development
'As a nonmedical professional, it is certainly to the authors' credit that these chapters are highly readable to nonmedical professionals who wish to develop a basic understanding of co-morbidity in autism.'
Karen Levine, American Association on Mental Retardation
'The voyage through biochemistry, immunology structural information and genetics is fascinating and the most comprehensive I have seen. It is an essential text for interested professionals.'
Paul Gringras, Autism
'There is much to recommend this book. There is a clear guide to the classification of autistic syndromes and diagnostic criteria with advice on practical application.'
Mark Hunter, Archives of Disease in Childhood
'The field of autism has seen an increase in research and literature in the last few decades. This book is an updated edition providing a detailed account of the latest research in the neuroimaging, genetics, and biochemistry of autism. It also addresses the diagnostic issues in autistic disorders, which is a matter of much controversy. The authors view autism as a neurodevelopmental process with a neurobiological insult to the brain occurring very early on in development, very likely in fetal life. The field of autism and its related disorders is changing so rapidly that an updated edition has come at the right time. The relationship of autism to known medical diseases and genetic syndromes is very well covered. The authors view autism as a syndrome and not as a single disease entity emphasizing the critical role of an individualized evaluation in each unique case.'
Shiraz Butt, MD, Rush University Medical Center
'The chapter on the epidemiology of autism is one of the best in the book … the authors' commitment to the people with autism whom they treat and with whom they work is an inspiration to all readers.'
Diane Treadwell-Deering, Journal of American Academy of Child Adolescent Psychiatry
'Clinicians will be well served by the Gillberg and Coleman book, and even serious students need to heed its message regarding the biological heterogeneity of autism, even in behaviourally well defined groups.'
Isabelle Rapin, European Journal of Paediatric Neurology
'A comprehensive reference book as well as stimulating reading for various disciplines as such as electrophysiology, neuropathology, and brain imaging.'
Journal of Neurol Neurosurg Psychiatry