Books

Subject: Neurodevelopmental Disorders and Neurodisability

Series: Clinics in Developmental Medicine

Publication date: 01/01/2005

ISBN: 9781898683384

Edition: 1st

Pages: 372

Central Nervous System Tumours of Childhood

Eddy Estlin, Stephen Lowis (Editors)

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Ranging from epidemiology and neuroimaging through the general principles of surgery and radiotherapy/chemotherapy to issues of palliative care and quality of life, this concise, broad-ranging and practical text covers all clinical aspects of central nervous system tumours in children.

It provides an overview of current important issues in diagnosis and management, and focuses on important areas of research, with an emphasis on the areas likely to impact on clinical practice.

It is essential reading for paediatric oncologists, medical and clinical oncologists, neurosurgeons, and paediatricians involved in the care of children with brain tumours, trainees in these and related specialties, specialist nurses and paramedical staff.

Clinics in Developmental Medicine No. 166

Eddy Estlin

Eddy Estlin is the Macmillan Consultant in Paediatric Oncology at the Royal Manchester Children’s Hospital, Manchester,  UK.

Stephen Lowis

Stephen Lowis is the Macmillan Consultant in Paediatric Oncology at the Hospital for Sick Children, Bristol, UK.

AUTHORS’ APPOINTMENTS vii
SECTION ONE: INTRODUCTION AND OVERVIEW OF DIAGNOSIS, 1
BIOLOGY AND THERAPY
1. INTRODUCTION 3
Eddy Estlin and Stephen Lowis
2. THE EPIDEMIOLOGY OF PAEDIATRIC CNS TUMOURS 7
GA Amos Burke
3. PAEDIATRIC CNS TUMOURS: NEUROIMAGING 18
Shelley Renowden
4. PATHOLOGY AND MOLECULAR ONCOLOGY OF CHILDHOOD 107
CNS TUMOURS
Lucy B Rorke-Adams and Jaclyn A Biegel
5. MOLECULAR APPROACHES TO THE UNDERSTANDING AND
TREATMENT OF CHILDHOOD CNS TUMOURS 129
Richard J Gilbertson
6. SURGICAL MANAGEMENT OF CNS TUMOURS IN THE
PAEDIATRIC POPULATION 151
Jerard Ross and John Thorne
7. GENERAL PRINCIPLES OF RADIOTHERAPY 163
Eddy Estlin and Stephen Lowis
8. GENERAL PRINCIPLES OF CHEMOTHERAPY 178
Eddy Estlin
9. MANAGEMENT OF COMPLICATIONS AT PRESENTATION FOR
CHILDREN WITH CNS TUMOURS 190
Stephen Lowis
SECTION TWO: CNS TUMOURS OF CHILDHOOD 201
10. LOW-GRADE AND HIGH-GRADE ASTROCYTOMA 203
Eddy Estlin and Stephen Lowis
11. EPENDYMOMA 221
Ute Bartels, Douglas J Hyder, Annie Huang and Eric Bouffet
12. BRAINSTEM TUMOURS 234
Carolyn R Freeman and Jean-Pierre Farmer
13. PRIMITIVE NEUROECTODERMAL TUMOURS 245
Stephen Lowis
14. INTRACRANIAL GERM CELL TUMOURS 258
Susanne J Rogers and Frank H Saran
15. CHOROID PLEXUS PAPILLOMA AND CARCINOMA 273
Stephen Lowis
16. CRANIOPHARYNGIOMA 277
Eddy Estlin
17. MIXED NEURONAL TUMOURS 284
Eddy Estlin
18. SPINAL CORD TUMOURS IN CHILDREN 289
Douglas J Hyder, Peter B Dirks, Ute Bartels and Eric Bouffet
19. METASTATIC DISEASE AFFECTING THE CNS 287
Stephen Lowis
SECTION THREE: LATE EFFECTS, REHABILITATION AND PALLIATIVE
CARE 301
20. LATE EFFECTS OF CNS TUMOURS 303
Adam Glaser and Gary Butler
21. AN OVERVIEW OF CEREBRAL FUNCTIONING AND ITS
APPLICATION IN THE DEVELOPING BRAIN 314
Andrew Curran
22. PALLIATIVE CARE 331
Erica Mackie
SECTION FOUR: SUMMARY 343
23. CONCLUSIONS AND FUTURE DIRECTIONS 345
Eddy Estlin and Stephen Lowis
INDEX