Disorders of Neuronal Migration addresses the various aspects of neuronal migration disorders in an ordered way. It will help the clinician to acquire insight as well as proficiency in diagnosis. Individual chapters describe subgroups including: – lissencephalies – subependymal heterotopia – non-lissencephalic cortical dysplasias – anomalies of the corpus callosum – hemimegalencephaly – schizencephaly – polymicrogyria and – multisystem disorders with impaired migration such as chromosomal and metabolic syndromes.
International Review of Child Neurology Series No. 5
Authors’ Appointments vii
Peter G Procopis
Peter G Barth
1. Morphogenesis of the human cerebral cortex 1
V. S. Caviness Jr, T. Takahashi, R. S. Nowakowski and Robert Wood
2. Lissencephaly: the clinical and molecular genetic basis of diffuse malformations of neuronal migration 24
William B. Dobyns and Richard J. Leventer
3. Non-lissencephalic cortical dysplasias 58
Ruben I. Kuzniecky and Frederick Andermann
4. Periventricular gray matter heterotopia: a heterogenous group of malformations of cortical development 72
Richard J Leventer and William B Dobyns
5. Anomalies of the corpus callosum and cortical malformations 83
A. James Barkovich
6. Hemimegalencephaly 104
7. Schizencephaly 127
Giorgio Battaglia and Tiziana Granata
8. Syndromic cortical dysplasias: a review 135
Raoul CM Hennekam and Peter G Barth
9. Polymicrogyria: role of the excitotoxic damage 170
Pierre Gressens, A James Barkovich and Philippe Evrard
10. Fetal disruption as a cause of neuronal migration defects, 182
Peter G Barth
'I found this to be a very worthwhile book which provides an excellent overview of a challenging and increasingly important area of pediatric neurology.'
Developmental Medicine & Child Neurology
'This book is going to be a text of reference for neurologists and epileptologists no mater how many updated classifications of malformations of cortical development may arise.'
Infant & Child Development
'This is a typical review book of a relatively specific subject and it would serve as a good beginning for those interested in learning more about this group of neurological problems.'
Michael White, MD, Ochsner Clinic Foundation