Many neurodevelopmental deficits originate in the perinatal period and there is increasing awareness of the need to look to early life, including prenatal life, to understand the origins of cognitive development and risk of neurodegenerative and psychiatric diseases.
This comprehensive and authoritative book is structured in a logical way from pathology to clinical outcome. Throughout, information from the basic sciences is placed within the clinical context, and there is excellent use of illustrative figures and images. Written by leading obstetricians, neonatologists, paediatricians and pathologists, this volume collates the ever-increasing evidence, both pathological and epidemiological, for the critical role of the utero-placenta in neurodisability, both at term and preterm. It encapsulates new advances in antepartum and perinatal imaging, new clinical aspects of fetal compromise, recent evidence of endocrine, haematological and inflammatory origins of utero-placental dysfunction, and possible cerebro-protective interventions. This text is essential reading for everyone concerned with child development and the in-utero origins of neurological disability.
- Written by leading obstetricians, neonatologists, paediatricians and pathologists
- Discusses the role of placenta in the pathophysiology of CNS
- Examines recent evidence of endocrine, haematological and inflammatory origins of utero-placental dysfunction
- Reviews latest advances in antepartum and perinatal imaging
Obstetricians, neonatologists, pathologists and basic scientists.
Clinics in Developmental Medicine Series