Acquired Brain Injury in the Fetus and Newborn – Chapter 13: Seizures in the Term Newborn Infant (ebook)


Chapter 13 – Seizures in the Term Newborn Infant

Seizures occur more often during the neonatal period than at any other time in life. Hypoxic–ischemic encephalopathy (HIE) has repeatedly been shown to be the most common underlying etiology in term infants. The incidence of HIE is estimated to be around  2 or 3 per 1000 births in the developed world, but much higher in the developing world. In the population-based study by Ronen et al (1999) 42% of the neonatal seizures were seen after HIE. Other important causes in both studies were focal pathology such as perinatal stroke and intracranial haemorrhage. Intracranial infection, hypoglycemia, inborn error of metabolism, and brain malformation are additional important etiologies.

About the book

Given the tremendous advances in the last five years in the understanding of acquired neonatal brain injury and in the care of affected newborn infants, this book provides a timely review for the practising neurologist, neonatologist and pediatrician. The editors take a pragmatic approach, focusing on specific populations encountered regularly by the clinician. They begin by addressing aspects of fetal neurology and the interpretation of fetal imaging studies. They then follow a ‘bench to bedside‚’ approach to acquired brain injury in the preterm and term newborn infant in the next chapters. The contributors, all internationally recognized clinician scientists, provide the clinician reader with a state-of-the art review in their area of expertise. The final section of the book address special populations and concerns, areas that are largely overlooked in existing neurology textbooks. Each of these areas has seen considerable advances in the last five years and is of increasing relevance to the neurologist and neonatologist clinician. The comprehensive nature of each section (from basic science to acute clinical care to outcomes) should appeal broadly to scientists and allied health professionals working in neonatal neurology.

Readership: Paediatric neurologists, neonatologists, neurologists and paediatricians, clinicians in child development, child health researchers and allied health professionals (in physiotherapy, occupational therapy, speech therapy and psychology).† Trainees in these areas.

International Reviews of Child Neurology Series No. 13