ICNA 5 Barth Disorders

Disorders of Neuronal Migration

Product Type: Print Edition (Complete Book)

ISBN: 9781898683315

Peter G. Barth (Editor)

Series: International Reviews of Child Neurology Series

Edition: 1st

Publication date: July 2003

Page count: 205

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Disorders of Neuronal Migration addresses the various aspects of neuronal migration disorders in an ordered way. It will help the clinician to acquire insight as well as proficiency in diagnosis. Individual chapters describe subgroups including: – lissencephalies – subependymal heterotopia – non-lissencephalic cortical dysplasias – anomalies of the corpus callosum – hemimegalencephaly – schizencephaly – polymicrogyria and – multisystem disorders with impaired migration such as chromosomal and metabolic syndromes.

International Review of Child Neurology Series No. 5

Peter G. Barth (Editor)


Peter G. Barth is Professor in Paediatric Neurology in the  Department of Paediatric Neurology, Emma Children's Hospital and the Academic Medical Center, University of Amsterdam, the Netherlands.

  • Authors' Appointments vii
  • Foreword ix
  • Peter G Procopis
  • Preface xi
  • Peter G Barth
  • 1. Morphogenesis of the human cerebral cortex 1
  • V. S. Caviness Jr, T. Takahashi, R. S. Nowakowski and Robert Wood
  • 2. Lissencephaly: the clinical and molecular genetic basis of diffuse malformations of neuronal migration 24
  • William B. Dobyns and Richard J. Leventer
  • 3. Non-lissencephalic cortical dysplasias 58
  • Ruben I. Kuzniecky and Frederick Andermann
  • 4. Periventricular gray matter heterotopia: a heterogenous group of malformations of cortical development 72
  • Richard J Leventer and William B Dobyns
  • 5. Anomalies of the corpus callosum and cortical malformations 83
  • A. James Barkovich
  • 6. Hemimegalencephaly 104
  • Laura Flores-Sarnat
  • 7. Schizencephaly 127
  • Giorgio Battaglia and Tiziana Granata
  • 8. Syndromic cortical dysplasias: a review 135
  • Raoul CM Hennekam and Peter G Barth
  • 9. Polymicrogyria: role of the excitotoxic damage 170
  • Pierre Gressens, A James Barkovich and Philippe Evrard
  • 10. Fetal disruption as a cause of neuronal migration defects, 182
  • Peter G Barth
  • Index 195

'I found this to be a very worthwhile book which provides an excellent overview of a challenging and increasingly important area of pediatric neurology.' Developmental Medicine & Child Neurology

'This book is going to be a text of reference for neurologists and epileptologists no mater how many updated classifications of malformations of cortical development may arise.' Infant & Child Development

'This is a typical review book of a relatively specific subject and it would serve as a good beginning for those interested in learning more about this group of neurological problems.' Michael White, MD, Ochsner Clinic Foundation