Clinics in Developmental Medicine Archives | Page 7 of 9

Developing Human Brain

Well over 200 illustrations, many in colour
Co-authored by two experts in neuropathology and neuroimaging
Takes a quantitative approach to brain growth in weight, gyrus formation, myelination, and spectroscopy of the developing brain
The only book in this field to include chapters in angiogenesis, fetal behaviour, and reactions to chronic illness

This book is about human brain development, focusing on the last half of gestation and the neonatal and infant periods. These periods bring the greatest risk for the acquisition of childhood functional neurologic deficits, including cerebral palsy, developmental delay and intellectual disability.

Section 1 covers typical development, including growth in brain weight, ventricular surfaces, gyral development, myelinated tract development, magnetic resonance spectroscopy, and angiogenesis, all serving as reference points for section 2, which deals with common acquired brain abnormalities, some of which are often underemphasized or overlooked.

The topics in section 2 include retrocerebellar cysts, abnormal events in fetal brain, white-matter abnormalities, lesions of gray and white matter, hemorrhage, ventriculomegaly and hydrocephalus, late expressions of fetal brain disease, and reactions of the developing brain to chronic disease. Between sections 1 and 2 is a chapter on embryonic and fetal physiologic reactions to external stimuli.

Where appropriate, the authors have combined pathologic with neuroimaging examples to help the reader better understand the neuroimages that they encounter.

Much of the information in the book is based on data from the National Collaborative Perinatal Project, still the only large autopsy survey of late fetal brain lesions.

Readership
Developmental neurobiologists, neuroscientists, paediatricians, neuropathologists, pediatric neuroradiologists, pediatric neurologists, neonatologists, perinatologists.

Clinics in Developmental Medicine No. 193

Development of Mature Walking

This important monograph summarizes a comprehensive study on the maturation of walking in normal children. Data are presented on anthropometric measurements; tests of developmental progress; time/distance parameters such as stride length and walking velocity; twelve joint angles on each side measured throughout the gait cycle; dynamic electromyography of phasic activity in seven lower-extremity muscle groups; and force measurements including vertical force, fore/aft shear, medial/lateral shear and torque. At each age, composite joint-angle graphs and time/distance parameters are brought together with film tracings of a representative child in that age group. In addition, advanced methods of statistical analysis have been applied to the joint-angle data to define prediction regions within which ninety-five percent of normal children should lie throughout the gait cycle. Finally, a ‘decision tree’ is presented from which a fitted age can be inferred for a subject based on non-age-specific data gathered in a motion analysis lab. Practical applications are demonstrated in a chapter devoted to two case studies.

Clinics in Developmental Medicine N0.104-105

Developmental Examinations of Infant and Preschool Children

This practical guide is for primary-care doctors and health visitors involved in the detection of developmental problems in children whose parents are worried that their child is not developing like other children. It will be of assistance to paediatricians and paediatric neurologists in providing a developmental perspective in the diagnostic process in their work with children with chronic neurological disorders. The tests described have been standardized by the author and cover the essentials of developmental examination: history–including parents’ views of their child’s development; clinical tests of hearing; examination of visual behavior and visual acuity; observation of developing motor skills; language/performance profiles in which any substantial unevenness or an overall low score may reveal a developmental problem. In practice the range of average ability is wide, so a distinctive feature of this book is a standardized data base in graphical form that can be used to identify readily those children (lowest twenty percent) who warrant further specialist investigation or treatment. It is particularly relevant today when general practitioners are being directed to take an active role in such preventive work.

Clinics in Developmental Medicine No.112

Developmental Screening and the Child with Special Needs

This book is the outcome of many years’ study on the large population of preschool children in Dundee, Scotland, where, since 1973, there has been an extensive and comprehensive program of development screening. The research population numbered more than 5,000 children, and the aims of the study were to estimate the frequency and types of neurodevelopmental disabilities identified, to describe their management, to attempt to ascertain causative factors, and to look at the predictive value of screening and its therapeutic value. This book is essential reading for all concerned with the planning or implementation of screening and surveillance programs for preschool children, and should finally answer the question of whether or not screening is worth while.

Clinics in Developmental Medicine No.86

Central Nervous System Tumours of Childhood

Ranging from epidemiology and neuroimaging through the general principles of surgery and radiotherapy/chemotherapy to issues of palliative care and quality of life, this concise, broad-ranging and practical text covers all clinical aspects of central nervous system tumours in children.

It provides an overview of current important issues in diagnosis and management, and focuses on important areas of research, with an emphasis on the areas likely to impact on clinical practice.

It is essential reading for paediatric oncologists, medical and clinical oncologists, neurosurgeons, and paediatricians involved in the care of children with brain tumours, trainees in these and related specialties, specialist nurses and paramedical staff.

Clinics in Developmental Medicine No. 166

Cerebellar Disorders in Children

This comprehensive clinically orientated text by an international group of experts is the first definitive reference book on disorders of the cerebellum in children. An invaluable resource for all those caring for children affected by cerebellar disorders, it presents a wealth of practical clinical experience backed up by a strong scientific basis for the information and guidance given.

The first part sets out the theoretical underpinnings of cerebellar disorders. This is followed by sections on clinical conditions grouped according to common characteristics such as aetiology and symptomatology. The descriptions of the clinical conditions each systematically cover, as appropriate, epidemiology, prevalence, diagnostic criteria, clinical features (including course and prognosis), pathophysiology, genetics, investigations, differential diagnosis, and management and treatment.

The book includes chapters on cerebellar development, prenatal cerebellar imaging, imaging of the posterior fossa, with coverage of a broad range of malformations, genetic and metabolic disorders involving the cerebellum, prenatal cerebellar disruptions (as related to prematurity), vascular disorders, tumors and paraneoplastic syndromes, as well as acute ataxia and trauma to the posterior fossa. Numerous checklists are provided to assist in the differential diagnosis of clinical signs and neuroimaging findings.

Readership
Paediatric neurologists, paediatricians, neurologists, developmental paediatricians, neuroimaging specialists, geneticists, neonatologists

Clinics in Developmental Medicine No. 191-192

Childhood Headache, 2nd Edition

Headache as a common problem which has a significant impact on children’s quality of life. This book provides practising clinicians with a comprehensive source of advice and knowledge on the diagnosis and management of childhood headache disorders. It addresses the needs of clinicians looking after children with headache, whether it was in a primary care setting, a hospital general paediatric clinic or in a specialist paediatric neurology service.

Assessment of the child with chronic headache takes a central position, with two chapters to help early diagnosis of the child with a serious neurological disorder. The scientific basis of headache and migraine is clearly presented and simplified in the chapter of pathophysiology. Many clinical cases are presented to illustrate the complexity, the importance or the rarity of certain headache disorders and bring to life the relevant models of assessment and management. The book also highlights the results of recent research and provides critical analysis of commonly accepted classification of headache disorders and also provides pointers of future research needs.

Written by world experts who are leaders in the field of headache in children, giving a global perspective
Authors brings their clinical experience to life with real case vignettes
The only book of its kind to maintain an excellent balance of clinical focus and research
Explores the current evidence base into the causes and treatments of childhood headache
The clinical recommendations are applicable anywhere in the world
The book is easy to read and fully referenced

Readership

A comprehensive source of knowledge and guidance to practising clinicians looking after children with headache which includes many clinical examples to illustrate the difficulties in diagnosis or options for treatment. It is also a resource for researchers who are looking for a full analysis of the published studies.

Clinics in Developmental Medicine Series

Aicardi’s Diseases of the Nervous System in Childhood, 4th Edition

The Premier Reference Book on Clinical Child Neurology

Congenital or early-onset disorders of the nervous system have a profound and lifelong impact on the lives of children and their families. Aicardi’s Diseases of the Nervous System in Childhood, 4th Edition provides up-to-date information on the full range of these neurological disorders, from fetal and neonatal neurology to adolescence.

Movement disorders, epilepsies and seizure disorders, metabolic diseases, auditory and visual disorders, and genetic anomalies are among the many topics covered in this text. Extensive reference lists at the end of each chapter guide the clinician to further relevant reading.

This fourth edition retains the patient-focussed, clinical approach of its predecessors. The international team of editors and contributors has honoured the request of the late Jean Aicardi, that his book remain ‘resolutely clinical’, which distinguishes Aicardi’s Diseases of the Nervous System in Childhood from other texts in the field. For further information about the history of this title and previous editions, please see Further Materials.

This edition:

Is completely revised and updated

Includes latest developments in genetic advances

Contains new chapters on basal ganglia diseases and psychogenic disorders

Has an easy-to-use one volume format with full-colour illustrations

Aicardi’s Diseases of the Nervous System in Childhood, 4th Edition remains the classic, user-friendly resource for busy clinicians in paediatric neurology, child neurology, general paediatrics, neurodisability, and all related medical disciplines.

Clinics in Developmental Medicine

Alcohol, Drugs and Medication in Pregnancy

Exposure to intrauterine drugs, alcohol and medicines can have profound effects on the child’s behaviour and propensity to behavioural disturbances. Some agents alter anatomic structure; others alter the chemical balance of neurotransmitters and may thus alter the regulation of brain function. This book documents the outcome and consequences for children exposed to intrauterine drugs, alcohol and medicine and explores strategies to support these children and those who care for them, including statutory agencies.

The international team of contributors sets out to inform the reader of the potential risks to infants exposed to a range of intrauterine chemicals that are potentially neuroactive, including medicinal drugs such as antiepileptics, antidepressants and antipsychotics, as well as drugs of abuse, including alcohol, opiates, and recreational drugs such as cannabis and tobacco. They review the teratogenic action of some of the chemical processes and the relationship of exposure to the stage of pregnancy.

In setting out the evidence for outcomes, the authors demonstrate that decisions about future care and management can and should be made early, with a secure understanding of the effect of this early exposure. This should allow professionals to provide protective management and prevent the delays in intervention and decision making that have so often been seen in this area of medical and social care.

Demonstrates the consequences for the child of alcohol and drugs in pregnancy
Includes chapters on the diagnosis and management of fetal alcohol syndrome
Explores strategies to support affected children and those who care for them

Readership

Paediatricians, neonatologists, obstetricians, gynaecologists, child and adolescent psychiatrists and psychologists, those working in child care and child protection.

Clinics in Developmental Medicine No. 188

Alcohol, Drugs and Young People

A comprehensive book dealing with drug, tobacco and alcohol abuse in both children and young people.

Presents the facts of drug and alcohol abuse, evidence for prevention and treatment, and reviews of the various types of treatments
Reviews all drugs of abuse, including tobacco and alcohol
Offers a practical presentation of evidence from particular therapies, such as cognitive behavioural therapy and family therapy
Presents a comprehensive review of the pharmacological advances for this age group with substance use disorders and other mental health problems
Written by an international team of professionals and academics, each with a background in adolescent development as well as addiction.

Clinics in Developmental Medicine No. 172