Acquired Brain Injury in the Fetus and Newborn – Chapter 1: Brain Injury in the Fetus (free ebook)


Chapter 1 – Brain Injury in the Fetus by Adre du Plessis from Acquired Brain Injury in the Fetus and Newborn

Normal fetal brain development may be disrupted by primary disturbances in its genetic blueprint, or by internal and external environmental factors. Antenatal influences may also predispose the fetal brain to injury during the intrapartum period. A review of primary brain dysgenesis is beyond the scope of this chapter, and intrapartum brain injury has been reviewed exhaustively elsewhere. The focus of this chapter is therefore confined to fetal brain injury occurring prior to intrapartum events.

About the Complete Book

Given the tremendous advances in the last five years in the understanding of acquired neonatal brain injury and in the care of affected newborn infants, this book provides a timely review for the practising neurologist, neonatologist and pediatrician.

The editors take a pragmatic approach, focusing on specific populations encountered regularly by the clinician. They begin by addressing aspects of fetal neurology and the interpretation of fetal imaging studies. They then follow a ‘bench to bedside‚’ approach to acquired brain injury in the preterm and term newborn infant in the next chapters.

The contributors, all internationally recognized clinician scientists, provide the clinician reader with a state-of-the art review in their area of expertise. The final section of the book address special populations and concerns, areas that are largely overlooked in existing neurology textbooks. Each of these areas has seen considerable advances in the last five years and is of increasing relevance to the neurologist and neonatologist clinician. The comprehensive nature of each section (from basic science to acute clinical care to outcomes) should appeal broadly to scientists and allied health professionals working in neonatal neurology.


Paediatric neurologists, neonatologists, neurologists and paediatricians, clinicians in child development, child health researchers and allied health professionals (in physiotherapy, occupational therapy, speech therapy and psychology). Trainees in these areas.

International Review of Child Neurology Series No. 13

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