Acquired Brain Injury in the Fetus and Newborn – Chapter 12: Protecting the Brain in Term Infants (ebook)


Chapter 12 – Protecting the Brain in Term Infants

There are many causes of brain injury in the term infant, including stroke, birth trauma, status epilepticus, metabolic or genetic disorders, and a variety of events resulting in hypoxia and ischemia. Hypoxic–ischemic encephalopathy (HIE) occurs in 3 to 5 in 1000 live births, while stroke has an incidence of 1 in 4000 live births. Many infants with perinatal brain injury die during early life, and the majority of survivors exhibit long-term neurologic deficits, which include intellectual disability, cerebral palsy, and epilepsy. When hypoxic–ischemic injury occurs in preterm infants it leads to periventricular white matter damage, whereas term infants develop cortical/subcortical lesions.

About the book

Given the tremendous advances in the last five years in the understanding of acquired neonatal brain injury and in the care of affected newborn infants, this book provides a timely review for the practising neurologist, neonatologist and pediatrician. The editors take a pragmatic approach, focusing on specific populations encountered regularly by the clinician. They begin by addressing aspects of fetal neurology and the interpretation of fetal imaging studies. They then follow a ‘bench to bedside‚’ approach to acquired brain injury in the preterm and term newborn infant in the next chapters. The contributors, all internationally recognized clinician scientists, provide the clinician reader with a state-of-the art review in their area of expertise. The final section of the book address special populations and concerns, areas that are largely overlooked in existing neurology textbooks. Each of these areas has seen considerable advances in the last five years and is of increasing relevance to the neurologist and neonatologist clinician. The comprehensive nature of each section (from basic science to acute clinical care to outcomes) should appeal broadly to scientists and allied health professionals working in neonatal neurology.

Readership: Paediatric neurologists, neonatologists, neurologists and paediatricians, clinicians in child development, child health researchers and allied health professionals (in physiotherapy, occupational therapy, speech therapy and psychology).† Trainees in these areas.

International Reviews of Child Neurology Series No. 13