Acquired Brain Injury in the Fetus and Newborn – Chapter 19: The Nutritionally Deprived Fetus and Newborn Infant (ebook)


Chapter 19 – The Nutritionally Deprived Fetus and Newborn Infant

The brain undergoes one of its most rapid periods of growth and differentiation during late fetal and neonatal life. As such, the metabolic, and thus nutrient, demands of the organ during this time period are high. The human brain has particularly high substrate requirements as it commands a greater percentage of total body energy consumption than any other mammal. It has been estimated that greater than 50% of fetal and neonatal energy expenditure is consumed by the brain. Preservation of substrate delivery to the brain is thus of paramount importance, and failure to accomplish this goal results in significant risks to neurodevelopment.

About the book

Given the tremendous advances in the last five years in the understanding of acquired neonatal brain injury and in the care of affected newborn infants, this book provides a timely review for the practising neurologist, neonatologist and pediatrician. The editors take a pragmatic approach, focusing on specific populations encountered regularly by the clinician. They begin by addressing aspects of fetal neurology and the interpretation of fetal imaging studies. They then follow a ‘bench to bedside‚’ approach to acquired brain injury in the preterm and term newborn infant in the next chapters. The contributors, all internationally recognized clinician scientists, provide the clinician reader with a state-of-the art review in their area of expertise. The final section of the book address special populations and concerns, areas that are largely overlooked in existing neurology textbooks. Each of these areas has seen considerable advances in the last five years and is of increasing relevance to the neurologist and neonatologist clinician. The comprehensive nature of each section (from basic science to acute clinical care to outcomes) should appeal broadly to scientists and allied health professionals working in neonatal neurology.

Readership: Paediatric neurologists, neonatologists, neurologists and paediatricians, clinicians in child development, child health researchers and allied health professionals (in physiotherapy, occupational therapy, speech therapy and psychology).† Trainees in these areas.

International Reviews of Child Neurology Series No. 13