Epilepsy-Aphasia Spectrum – Chapter 11: Functional Neuroimaging Investigations in Idiopathic Focal Epilepsies of Childhood with Cognitive and Behavioural Impairment (ebook)
Chapter 11 – Functional Neuroimaging Investigations in Idiopathic Focal Epilepsies of Childhood with Cognitive and Behavioural Impairment
In this chapter, we will present how functional neuroimaging techniques have been used to non-invasively address the pathophysiological link between IEDs and the acquired cognitive and behavioural regression typically observed in cognitive epilepsies. Considering the clinical similarities between the different epileptic syndromes encompassed by cognitive epilepsies, most of the functional neuroimaging studies have pooled together patients with different epileptic syndromes that have as a common feature an increase in the frequency, amplitude and diffusion of IEDs occurring during non-REM sleep (Landau-Kleffner syndrome , ARE and EE with CSWS) in order to derive the common changes in brain function characterizing these epileptic conditions.
About the book
Landau Kleffner syndrome (LKS) is a rare childhood epilepsy, characterised by a sudden or gradual loss of ability to understand or express language. Written by two world-renowned authorities on childhood epilepsy, this book is aimed at the large range of professionals involved in the diagnosis, therapy and rehabilitation of children on the EAS. The book includes vivid first-hand accounts of the impact of language loss by adults who have grown up with LKS.
Readership: epileptologists, psychiatrists, psychologists, neuropsychologists, speech and language therapists and trainees in those areas.