Cerebellar Disorders in Children – Chapter 33: Posterior Fossa Tumours (ebook)


Chapter 33 – Posterior Fossa Tumours

Michael A. Grotzer

Brain tumours are the most common solid tumours in children (Gurney and Kadan-Lottick 2001). The leading cause of cancer-related morbidity and mortality in children, they differ from primary central nervous system (CNS) tumours occurring in adults in histology, localization, management, and prognosis (Merchant et al. 2010). Because the developing brain is highly vulnerable to treatment-induced cognitive and endocrine sequelae, particularly from radiotherapy, contemporary strategies for the management of childhood brain tumours incorporate both age-specific and histology-specific approaches. Ongoing studies focus not only on the duration, but also on the quality of survival (Packer 2008).

Please note that Chapters 32-35 are also available in Part 7: Vascular Disorders, Tumours, and Paraneoplastic Cerebellar Syndromes.

About the Complete Book:

This clinically orientated text by an international group of experts is the first definitive reference book on disorders of the cerebellum in children. It presents a wealth of practical clinical experience backed up by a strong scientific basis for the information and guidance given. The first part sets out the theoretical underpinnings of cerebellar disorders. This is followed by sections on clinical conditions grouped according to common characteristics such as aetiology and symptomatology. The descriptions of the clinical conditions each systematically cover, as appropriate, epidemiology, prevalence, diagnostic criteria, clinical features (including course and prognosis), pathophysiology, genetics, investigations, differential diagnosis, and management and treatment. This book will be an invaluable resource for all those caring for children affected by cerebellar disorders, including malformations, genetic and metabolic disorders, acquired cerebellar damage, vascular disorders and acute ataxias. This comprehensive reference text on cerebellar disorders in children includes chapters on cerebellar development, prenatal cerebellar imaging, imaging of the posterior fossa, with coverage of a broad range of malformations, genetic and metabolic disorders involving the cerebellum, prenatal cerebellar disruptions (as related to prematurity), vascular disorders, tumors and paraneoplastic syndromes, as well as acute ataxia and trauma to the posterior fossa. Numerous checklists are provided to assist in the differential diagnosis of clinical signs and neuroimaging findings.

Paediatric neurologists, paediatricians, neurologists, developmental paediatricians, neuroimaging specialists, geneticists, neonatologists

Clinics in Developmental Medicine No. 191-192