Cerebral Palsy: Science and Clinical Practice – Chapter 13: Non-Inflammatory and Non-Endocrine Pathways from Preterm Birth to Cerebral Palsy (ebook)


Chapter 13 of the book – Non-Inflammatory and Non-Endocrine Pathways from Preterm Birth to Cerebral Palsy

Steven J Korzeniewski and Athina Pappas

This chapter consists of probabilistic thinking about noninflammatory and non-endocrine characteristics of preterm infants (born at <37 wk gestation) that may lead to cerebral palsy (CP). Inflammatory antecedents of CP are covered in Chapter 9, and endocrine antecedents in Chapter 12. Identification of deterministic pathways is challenging in light of the many competing risk factors for CP that are common in preterm infants. These include maternal and pregnancy-related complications such as infections, placental problems, and maternal disease states; multi-organ immaturity; inadequacy of protective substances such as hormones, growth factors and nutrients; and the structural vulnerability and postnatal physiologic instability characteristic of the preterm infant.

About the complete book

This landmark title considers all aspects of cerebral palsy from the causes to clinical problems and their implications for individuals. An international team of experts provides clinicians and researchers with key information on the mechanisms underlying impairments in movement, development, cognition, communication, vision, feeding, behaviour, sexuality, and musculoskeletal deformities.  They present a wide range of person-centred assessment approaches, including clinical evaluation, measurement scales, neuroimaging and gait analysis. The principles of multi-disciplinary management are presented, in terms of therapist intervention, medication and surgery. The perspective of the book spans the lifelong course of cerebral palsy, taking into account worldwide differences in socio-economic and cultural factors. Many chapters are illustrated with clinical vignettes enabling direct translation into practice. Full integrated colour, with extensive cross-referencing make this a highly attractive and useful reference.

Readership: Paediatric neurologists, developmental paediatricians, rehabilitation doctors, orthopaedic surgeons, child psychiatrists, physiotherapists speech and language therapists psychologists, occupational therapists and other health and educational professionals.

Clinics in Developmental Medicine Series.