Cognition and Behaviour in Childhood Epilepsy – Chapter 11: Infantile Spasms: Early Treatment may Improve Neurodevelopmental Outcomes (ebook)


Chapter 11 РInfantile Spasms: Early Treatment may Improve Neurodevelopmental Outcomes

Infantile spasms is the term given to the most common epilepsy syndrome with onset in infancy. It has been the focus of many studies, in part because of the high probability of children with infantile spasms having poor neurodevelopmental outcomes. In considering the possible effects of infantile spasms upon cognition and behaviour, both during the period in which clinical epileptic spasms are occurring and during subsequent life, it is essential to consider several factors and relationships related to their pathophysiology. The most important of these are (1) the nature of the probable underlying cause (or aetiology) for the infantile spasms; (2) the effects that any identified aetiology might have upon the proneness to infantile spasms or other forms of epilepsy, and upon longer term prospects for development; and (3) the causal relationships that are known to exist or might exist between aetiology, the epileptic spasms, and neurodevelopmental outcomes. It is also important to consider questions related to treatment interventions, the key questions being (1) which treatment interventions are most likely to lead to the best cognitive and behavioural outcomes and (2) what is the optimal timing for these interventions.

About the book

For many parents, cognitive and behavioral comorbidities, such as ADHD, autism and intellectual disability, are the real burden of childhood epilepsy. This title offers concrete guidance and treatment strategies for childhood epilepsy in general, and for the comorbidities associated with each epilepsy syndrome and their pathophysiology. The book is written by experts in the field with an important clinical experience, while chapters by clinical neuropsychologists provide a strong theoretical background.

Readership: Epileptologists, Paediatric Neurologists, Paediatricians and Neuropsychologists.