Cognition and Behaviour in Childhood Epilepsy – Chapter 14: Global Prognosis And Neuropsychological Outcome Of Lennox–Gastaut Syndrome (ebook)


Chapter 14 – Global Prognosis And Neuropsychological Outcome Of Lennox–Gastaut Syndrome

Lennox–Gastaut syndrome (LGS) is a severe and chronic epileptic encephalopathy with onset in early childhood. Following the medical thesis of Dr. Charlotte Dravet (1965), described in Epilepsia a childhood-onset epilepsy type characterized by the progressive appearance of several types of seizures (including tonic seizures particularly during sleep), associated with EEG tracings to an interictal pattern of diffuse spike–wave complexes and 10Hz discharges often translating tonic events during slow sleep and neurodevelopmental regression. Several publications followed and LGS was adopted by the International League Against Epilepsy Classification Commission in 1989. However, the nosological uncertainty surrounding the syndrome persisted and the term LGS is, even today, applied rather loosely.

About the book

For many parents, cognitive and behavioral comorbidities, such as ADHD, autism and intellectual disability, are the real burden of childhood epilepsy. This title offers concrete guidance and treatment strategies for childhood epilepsy in general, and for the comorbidities associated with each epilepsy syndrome and their pathophysiology. The book is written by experts in the field with an important clinical experience, while chapters by clinical neuropsychologists provide a strong theoretical background.

Readership: Epileptologists, Paediatric Neurologists, Paediatricians and Neuropsychologists.