Neuroendocrine Disorders in Children – Chapter 1: Neuroendocrine Regulation of Growth Hormone Secretion (free ebook)


Chapter 1 – Neuroendocrine Regulation of Growth Hormone Secretion by Peter C Hindmarsh and Iain CAF Robinson from Neuroendocrine Disorders in Children 

The entire process of human growth represents a continuum to which birth is largely incidental. Postnatal growth can be considered to consist of at least three distinct phases: infancy, childhood and puberty. The infancy component is largely a continuation of the longitudinal growth process observed in utero. This displays a peak length velocity around 27 to 28 weeks of gestation, with a decline in growth rate during the last trimester of pregnancy. This declining growth rate continues during the first 3 years of life, reaching a plateau at or around the fourth year of life and continues at this rate until the commencement of the pubertal growth spurt.

About the Complete Book

Impairments in the interaction between the central nervous system and the endocrine system can lead to a number of disorders in children.  These include type 1 diabetes, growth disorders, adrenal thyroid and pituitary problems, Addison’s disease and Cushing syndrome, among others.

Neuroendocrine Disorders in Children provides a comprehensive examination of paediatric and adolescent disorders focusing on the basic science and its clinical relevance. Complex issues are discussed in an easy-to-follow manner and the latest developments in the area are reviewed.


Paediatric endocrinologists, paediatric and adult neurologists and trainee paediatricians.

Full Book Review

Read the full book review by Ieuan Hughes published in Developmental Medicine and Child Neurology.

Video from the Editor

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Clinics in Developmental Medicine Series

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