Neuroendocrine Disorders in Children – Chapter 13: Craniopharyngioma (ebook)
Chapter 13 – Craniopharyngioma
First described in 1857, craniopharyngiomas are benign non-gliomatous central nervous system (CNS) tumours (WHO classification grade I) originating from embryonal tissue in the hypothalamo-pituitary region. Although their incidence is rare (1.1–1.7 cases/million/year), craniopharyngiomas are the commonest suprasellar tumour in childhood, and contribute to 1.5%–11.6% of all paediatric CNS tumours. Despite their benign histology, their invasive nature and location close to vital hypothalamo-pituitary structures make them the archetypal suprasellar tumour for causing neuroendocrine dysfunction, not only due to invasion and mass effects, but also from treatments targeted to this area.
About the book
Impairments in the interaction between the central nervous system and the endocrine system can lead to a number of disorders in children. These include type 1 diabetes, growth disorders, adrenal thyroid and pituitary problems, Addison’s disease and Cushing syndrome, among others.
Neuroendocrine Disorders in Children provides a comprehensive examination of paediatric and adolescent disorders focusing on the basic science and its clinical relevance. Complex issues are discussed in an easy-to-follow manner and the latest developments in the area are reviewed.
Read the full book review by Ieuan Hughes published in DMCN.
Readership: paediatric endocrinologists, paediatric and adult neurologists and trainee paediatricians.