Neuroendocrine Disorders in Children – Chapter 22: Diabetes and the Developing Brain (ebook)


Chapter 22 – Diabetes and the Developing Brain

Glucose is the primary metabolic fuel for the central nervous system (CNS). Diabetes, particularly type 1 diabetes, is a chronic disease that primarily disrupts the stability of plasma glucose concentrations. Developing brains are more susceptible to metabolic insults than the mature CNS. Thus it is not surprising that type 1 diabetes during childhood and adolescence impacts upon neural and brain development. As the emphasis of diabetes care during childhood broadens from the avoidance of acute metabolic disturbance and microvascular complications such as renal and retinal disease, there is an increasing interest in the impact of diabetes upon the pre-eminent developmental task of childhood – that of CNS ontogeny.

About the book

Impairments in the interaction between the central nervous system and the endocrine system can lead to a number of disorders in children.  These include type 1 diabetes, growth disorders, adrenal thyroid and pituitary problems, Addison’s disease and Cushing syndrome, among others.

Neuroendocrine Disorders in Children provides a comprehensive examination of paediatric and adolescent disorders focusing on the basic science and its clinical relevance. Complex issues are discussed in an easy-to-follow manner and the latest developments in the area are reviewed.

Read the full book review by Ieuan Hughes published in DMCN.

Readership: paediatric endocrinologists, paediatric and adult neurologists and trainee paediatricians.